not being able to use Skype is a big problem

[Shawn Rutledge]

It's often been wished for an Asterisk-to-Skype gateway.  It would be
an elegant solution: run the gateway at home or on a hosted server,
and use any ordinary SIP or IAX client on the Neo.

Well last time I checked into that was a couple years ago, but now it
appears such a thing exists:

http://www.mhspot.com/mhspot/sippyskype.htm

https://extras.skype.com/categories/all/good/asterisk

http://blog.tmcnet.com/blog/tom-keating/skype/sip-to-skype-gateway-breaks-skypes-great-wall-of-voip.asp
http://www.asteriskvoipnews.com/asterisk_development/skypetoasterisksip_progress_part_1.html

And asterisk of course can make good use of third-party PSTN (real
telephone line) termination services, or you can use a Winmodem to
connect Asterisk to your own home phone line.  Then use the Neo as a
client.